ANALYSIS OF THE ENVIRONMENTAL TOXICITY OF ANTIPSYCHOTIC DRUGS USED IN THE TREATMENT OF PSYCHOSIS AND MENTAL DISORDERS

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Published: 2024-10-28
DOI: https://doi.org/10.5281/zenodo.14046131
Keywords:
Antipsychotics; Ecotoxicity; Pharmaceuticals in the environment; ECOSAR.

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Nícolas Viana
Universidade Santa Cecília, Faculdade de Ciências da Saúde, Curso de Farmácia Laboratório de Pesquisa em Produtos Naturais, Universidade Santa Cecília.
Luciana Guimarães
Universidade Santa Cecília, Faculdade de Ciências da Saúde, Curso de Farmácia Laboratório de Pesquisa em Produtos Naturais, Universidade Santa Cecília.

Abstract

The presence of pharmaceutical substances in the environment, including antipsychotic drugs, has raised global concern. These drugs, widely used to treat mental disorders, can enter the environment through therapeutic use, human and animal excretion, and improper disposal, contributing to environmental contamination. Antipsychotics can persist for long periods, posing potential toxic effects on organisms. This study aims to investigate the structure-activity and ecotoxicity relationships (ECOSAR) of 10 antipsychotic drugs through the analysis of their chemical markers and toxicity, utilizing the ECOSAR v1.11 software from the EPI Suite® v.4.11 platform.


 


Keywords: Antipsychotics; Ecotoxicity; Pharmaceuticals in the environment; ECOSAR.


 

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Article Details

Issue

Anais do Congresso Brasileiro de Iniciação Cientifica

Section

Artigos Ciências Biológicas e Ciências da Saúde
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