THE INFLUENCE OF OMEGA-3 ON THE PROGRESSION OF ALZHEIMER’S DISEASE

Abstract

Alzheimer’s Disease (AD) is a progressive neurodegenerative condition characterized by memory loss and cognitive and behavioral changes. Studies have investigated supplementation with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) to slow AD progression. This article aimed to evaluate the effect of omega-3 on the preservation of cognitive functions. The method consisted of a systematic review of articles published between 2010 and 2025 in the PubMed and Science Direct databases. Five studies reported increased serum DHA and EPA levels, with heterogeneous effects on memory and cognition—more evident in the early stages and when combined with other nutrients—with good tolerability. It was concluded that omega-3 alone has limited effects, but when initiated early and combined with other nutrients, it may help preserve cognition. Further studies are needed