In vitro susceptibility of Candida albicans to gallic acid and ellagic acid Leonardo Teixeira Ramos, Carmem Bianca Mecena do Espirito Santo, Carlos Antonio Spinosa Colatrelo, Luciana Lopes Guimarães

Abstract

Candida albicans is a yeast with a well-known pathogenic potential, with the ability to adhere to different mucous membranes and epithelia as the main factors of pathogenicity and virulence. The restricted number of antifungal classes currently available and the observed increase in resistance to these antifungals lead to a growing interest in research and development of new classes that act on different targets of the antifungals currently in use. In this context, the present study aimed to evaluate the in vitro antifungal activity of gallic acid and ellagic acid,  phenolic compounds naturally present in different plant species, in cultures of Candida albicans through the microdilution method.